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Releasing mosquitoes to control mosquitoes

Geneticist Luke Alphey and his team describe how they use genetically modified mosquitoes to reduce the number of mosquitoes that spread dengue fever

Figure 1 Female Aedes aegypti feeding on human blood

Virus Disease Dengue fever Gene cloning Recombinant DNA technology

Dengue fever is the fastest growing mosquito-borne disease — 50–100 million people are affected each year. It is a viral disease spread by female mosquitoes, and largely by females of just one species — Aedes aegypti. This mosquito takes blood mainly from humans (see Figure 1), and tends to live in and around people’s homes. Dengue can result in fever, headaches, tiredness and muscle and joint ache. In its more severe form — dengue haemorrhagic fever — the disease can be fatal. Four different but related viruses cause this disease. If a person becomes infected by one strain of virus, they can develop immunity to that strain, but then they become more susceptible to the three other strains. Infection with a second viral strain usually produces more severe symptoms.

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Previous

Learning from the long dead: beneath the mummies’ bandages

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Animals and the human pathogens they carry

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